Obesity-Associated Organ Damage and Sympathetic Nervous Activity
نویسندگان
چکیده
منابع مشابه
Sympathetic nervous system activity is associated with obesity-induced subclinical organ damage in young adults.
Excess weight is established as a major risk factor for cardiovascular diseases, particularly in young individuals. To get a better understanding of the pathophysiology underlying increased cardiovascular disease risk, we evaluated early signs of organ damage and their possible relationship to sympathetic nervous activity. Eighteen lean (body mass index <25 kg/m(2)) and 25 overweight or obese (...
متن کاملNervous System Sympathetic Nervous System Activity Is Associated With Obesity-Induced Subclinical Organ Damage in Young Adults
Excess weight is established as a major risk factor for cardiovascular diseases, particularly in young individuals. To get a better understanding of the pathophysiology underlying increased cardiovascular disease risk, we evaluated early signs of organ damage and their possible relationship to sympathetic nervous activity. Eighteen lean (body mass index 25 kg/m) and 25 overweight or obese (body...
متن کاملRelation of obesity and diet to sympathetic nervous system activity.
The hypothesis that dietary intake and obesity stimulate the sympathetic nervous system was investigated in a cross-sectional study of 572 men aged 43-85 years from the Normative Aging Study. Habitus was represented by body mass index, as a measure of overall adiposity, and by the ratio of abdomen-to-hip circumference (abdomen/hip ratio), as a measure of centripetal fat distribution. Sympatheti...
متن کاملRole of sympathetic nervous system and neuropeptides in obesity hypertension.
Obesity is the most common cause of human essential hypertension in most industrialized countries. Although the precise mechanisms of obesity hypertension are not fully understood, considerable evidence suggests that excess renal sodium reabsorption and a hypertensive shift of pressure natriuresis play a major role. Sympathetic activation appears to mediate at least part of the obesity-induced ...
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TO THE EDITOR: The increasing prevalence of human obesity is posing a major threat to global health. This concern has prompted great interest in the mechanisms responsible for the development of obesity. In their review paper, Nedergaard et al. (6) discuss the evidence indicating that the brown adipose tissue plays a significant and contributory role in the pathogenesis of human obesity through...
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ژورنال
عنوان ژورنال: Hypertension
سال: 2019
ISSN: 0194-911X,1524-4563
DOI: 10.1161/hypertensionaha.118.11676